PUBLICATIONS

*Co-first author #Co-corresponding author

• 2024 - Ronneau S#, Michaux C, Giorgio RT, Helaine S#. Intoxication of antibiotic persisters by host RNS inactivates their efflux machinery during infection. PLoS Pathog. 2024 Feb 29;20(2):e1012033. doi: 10.1371/journal.ppat.1012033. PMID: 38421944; PMCID: PMC10903880.

• 2023 - Ronneau S*, Michaux C*, Helaine S. Decline in nitrosative stress drives antibiotic persister regrowth during infection. Cell Host Microbe. 2023 Jun 14;31(6):993-1006.e6. doi: 10.1016/j.chom.2023.05.002. Epub 2023 May 25. PMID: 37236190.

• 2022 - Michaux C*, Ronneau S*, Giorgio RT, Helaine S. Antibiotic tolerance and persistence have distinct fitness trade-offs. PLoS Pathog. 2022 Nov 14;18(11):e1010963. doi: 10.1371/journal.ppat.1010963. PMID: 36374854; PMCID: PMC9704765.

• 2021 - Ronneau S, Hill PW, Helaine S. Antibiotic persistence and tolerance: not just one and the same. Curr Opin Microbiol. 2021 Dec;64:76-81. doi: 10.1016/j.mib.2021.09.017. Epub 2021 Oct 9. PMID: 34634678.

• 2021 - Hill PWS*, Moldoveanu AL*, Sargen M, Ronneau S, Glegola-Madejska I, Beetham C, Fisher RA, Helaine S. The vulnerable versatility of Salmonella antibiotic persisters during infection. Cell Host Microbe 2021 Dec 8; 29(12):1757-1773.

• 2021 - Michaux C*, Ronneau S*, Helaine S. Studying Antibiotic Persistence During Infection. Methods Mol Biol. 2021;2357:273-289. doi: 10.1007/978-1-0716-1621-5_18. Erratum in: Methods Mol Biol. 2021;2357:C1. doi: 10.1007/978-1-0716-1621-5_19. PMID: 34590265.

• 2019 - Ronneau S, Helaine S. Clarifying the Link between Toxin-Antitoxin Modules and Bacterial Persistence. J Mol Biol. 2019 Aug 23;431(18):3462-3471. doi: 10.1016/j.jmb.2019.03.019. Epub 2019 Mar 23. PMID: 30914294.

• 2019 - Ronneau S#, Hallez R#. Make and break the alarmone: regulation of (p)ppGpp synthetase/hydrolase enzymes in bacteria. FEMS Microbiol Rev. 2019 Jul 1;43(4):389-400. doi: 10.1093/femsre/fuz009. PMID: 30980074; PMCID: PMC6606846.

• 2019 - Ronneau S, Caballero-Montes J, Coppine J, Mayard A, Garcia-Pino A, Hallez R. Regulation of (p)ppGpp hydrolysis by a conserved archetypal regulatory domain. Nucleic Acids Res. 2019 Jan 25;47(2):843-854. doi: 10.1093/nar/gky1201. PMID: 30496454; PMCID: PMC6344854.

• 2016 - Ronneau S, Petit K, De Bolle X, Hallez R. Phosphotransferase-dependent accumulation of (p)ppGpp in response to glutamine deprivation in Caulobacter crescentus. Nat Commun. 2016 Apr 25;7:11423. doi: 10.1038/ncomms11423. PMID: 27109061; PMCID: PMC4848567.

• 2016 - Ronneau S, Moussa S, Barbier T, Conde-Álvarez R, Zuniga-Ripa A, Moriyon I, Letesson JJ. Brucella, nitrogen and virulence. Crit Rev Microbiol. 2016 Aug;42(4):507-25. doi: 10.3109/1040841X.2014.962480. Epub 2014 Dec 4. PMID: 25471320.

• 2015 - Strahl H, Ronneau S, González BS, Klutsch D, Schaffner-Barbero C, Hamoen LW. Transmembrane protein sorting driven by membrane curvature. Nat Commun. 2015 Nov 2;6:8728. doi: 10.1038/ncomms9728. PMID: 26522943; PMCID: PMC4632190.

All our publications can be found here : https://pubmed.ncbi.nlm.nih.gov/?sort=date&term=Ronneau%20S&cauthor_id=30980074

Illustration of our work (Ronneau, Michaux, and Helaine, 2023) by artist Marie Muravski. In our study, we demonstrated that some Salmonella are "locked" in a persister state that protects them from antibiotic treatment. By leveraging our knowledge, we described how to unlock these persisters to resensitize them to antimicrobials during infection. The original version of this painting is displayed on the wall of Dr. Sophie Helaine's office at Harvard Medical School, Boston.